Physical examination, International Prostate Symptom Score, quality of life (QoL), five-item version of the International Index of Erectile Function (IIEF-5), basic clinical chemistry parameters, haematology, Se, testosterone, PSA (free and total), C-reactive protein (CRP), antioxidant status, transrectal ultrasound prostate volume, urinary flow rate, ultrasound-estimated post-void residual urine volume at baseline, and at 3 and 6 months, and urine ex vivo anti-adherence activity were determined in all subjects. Forty-two participants received either 1500 mg of the dried powdered cranberries per d for 6 months (cranberry group n 21) or no cranberry treatment (control group n 21). The objective of the present study was to evaluate the efficacy and tolerability of cranberry ( Vaccinium macrocarpon) powder in men at risk of prostate disease with LUTS, elevated prostate-specific antigen (PSA), negative prostate biopsy and clinically confirmed chronic non-bacterial prostatitis. Lower urinary tract symptoms (LUTS) are a common condition in older men.
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